Mean platelet size: Looking at the chicken or the egg?

According to the WHO, in 2030, more than 23 million people will die annually as a result of cardiovascular disease (CVD). This will make it the leading cause of death worldwide. Although medicine has made huge steps in diagnostics (e.g., bio-markers, MRI, echocardiography) and therapy (e.g., antihypertensive drugs, platelet inhibitors, and cardiologic interventions, such as PCI), treatment of a disease will not be sufficient to reduce the burden of CVD.