Author/Authors :
López-Cancino, Sury Antonio Laboratory of Parasitology Research - Federico Gómez Children´s Hospital of Mexico, Mexico City, Mexico , Fernando Méndez-Galván, Jorge Unit of Emerging Infectious Diseases Research - Federico Gómez Children Hospital of Mexico, Mexico City, Mexico , Soria- Guerrero, Mariana Laboratory of Parasitology Research - Federico Gómez Children´s Hospital of Mexico, Mexico City, Mexico , Meneses-Mayo, Marcos Research Center of Health Sciences - Faculty of Health Sciences - Anahuac México University, State of México, México , Agustin Islas-Andrade, Sergio Research Center of Health Sciences - Faculty of Health Sciences - Anahuac México University, State of México, México , Jiménez- Cardoso, Enedina Laboratory of Parasitology Research - Federico Gómez Children´s Hospital of Mexico, Mexico City, Mexico
Abstract :
Congenital Chagas disease is considered a form of dispersion of Trypanosoma
cruzi related to human migration from endemic, often rural to previously nonendemic
urban areas. This fact increases the Chagas disease establishment risk
inside of family members by vertical transmission pathway. Congenital Chagas
disease cases in newborns could not identified by the health professional even
in endemic regions. Here we present the first family cluster of Chagas disease
cases from Chiapas: one of the most important endemic areas in South of Mexico,
where vertical T. cruzi transmission incidence rate is ranged between 2% to
22% revealing an important public health problem. Two cases inside a family
from Chiapas, México with positive antibodies against T. cruzi detected by ELISA
are presented; one of them got the infection through vertical pathway. We
think that congenital Chagas disease should not be ignored in a newborn born
from an asymptomatic Chagas disease mother, who may transmit the parasite
infection randomly.
Keywords :
Congenital Chagas disease , Trypanosoma cruzi , Pregnancy , Mexico
