Title of article :
Ribosome Profiling: A Useful Approach to Discover Hidden Corners of SARS-CoV-2
Author/Authors :
Zandi ، Milad Department of Virology - School of Public Health - Tehran University of Medical Sciences , Behboudi ، Emad Department of Microbiology - School of Medicine - Golestan University of Medical Sciences , Zeinali ، Parisa Department of Biochemistry and Biophysics - School of Medicine, Metabolic Disorders Research Center - Golestan University of Medical Sciences , Soltani ، Saber Department of Virology - School of Public Health - Tehran University of Medical Sciences , Shojaei ، Mohammad Reza Department of Microbiology - School of Medicine - Golestan University of Medical Sciences
Abstract :
Following SARS-CoV-2 China epidemic in the December 2019, researches have attended to the genome of novel coronavirus. Hidden corners of SARS-CoV-2, maybe a shiny way to discover its pathogenicity and virulence. To design therapeutic agents, it is critical to map the complete repertoire of viral-translated proteins. Ribosome profiling is considered as a snapshot of all active ribosomes in a cell at a specific time point.
Keywords :
Genome , Open Reading Frames , Ribo , seq , SARS , CoV , 2
Journal title :
Cell Journal (Yakhteh)
Journal title :
Cell Journal (Yakhteh)