Title of article :
Interleukin 6 (IL-6) in Patient with COVID-19 Infection: The Cross-Sectional Study
Author/Authors :
Karpians, Gevik Department of Biochemistry - Medical Laboratory, Tehran, Iran , Piranfar, Vahhab Research and Development Department - Farname Inc - Thornhill, Canada , Karami, Mina Department of Molecular Biology - Medical Laboratory, Tehran, Iran
Pages :
2
From page :
256
To page :
257
Abstract :
To update data published in the article “Leukocytes Parameters, CRP, and Ferritin in Iranian Patients with COVID-19 Infection; A Cross-sectional Study” in Iranian Journal of Medical Microbiology. 2021,15(3): 361-368 (1), we analyzed the IL-6 parameter in the article mentioned above’s statistical population (2, 3). Here, we share our new findings as a Letter to the editor. SARS-CoV-2 (coronavirus 2 or 2019-nCoV) can cause Cytokine release syndrome (CRS) (4). Many inflammatory cytokines are released in the body of patients with CRS due to leucocyte activation (5). IL-6 is a chemokine that has increased in CRS. Also, IL-6 stimulates the secretion of acute-phase proteins, such as C-reactive protein (CRP), ferritin, and fibrinogen, and inhibits albumin synthesis (6). Therefore, the increased IL-6 is a potential candidate as a biomarker for SARS-CoV-2 detection.
Keywords :
Interleukin 6 (IL-6) , Patient , COVID-19 , Medical Microbiology
Journal title :
Journal of Obstetrics, Gynecology and Cancer Research
Serial Year :
2022
Record number :
2717397
Link To Document :
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