Author/Authors :
Bartolia, Giuseppe Università di Bologna - Dipartimento di Chimica Organica ‘A Mangini’, Italy , De Nino, Antonio Università della Calabria - Dipartimento di Chimica, Italy , Dalpozzo, Renato Università della Calabria - Dipartimento di Chimica, Italy , Maiuolo, Loredana Università della Calabria - Dipartimento di Chimica, Italy , Nardi, Monica Università della Calabria - Dipartimento di Chimica, Italy , Procopio, Antonio Università della Magna Graecia (Cz) - Dipartimento di Scienze Farmaco-Biologiche, Italy , Tagarelli, Antonio Università della Calabria - Dipartimento di Chimica, Italy
Abstract :
Cerium is the less rare rare earth; its salts are commercially available and inexpensive. However,screening of lanthanide triflates as Lewis acid catalysts in the Friedel-Crafts acylation of aromatics skipped cerium triflate. Now, catalytic Friedel-Crafts acylations of activated benzenes are performed by using cerium (III) triflate as catalyst. For less activated arenes, addition of lithium perchlorate as co-catalyst is required. In all cases aromatic ketones are obtained in very good yields.
Keywords :
Electrophilic substitution , Lewis acid catalysis , anhydrides , arenes , lanthanide triflates , lithium perchlorate
