Study of the level of signal-regulated kinase 5 (ERK5) in patients with coronary heart disease with and without diabetes mellitus type 2

Diabetes mellitus (DM) is a complicated and varied metabolic disorder characterized by high blood glucose levels. Coronary heart disease (CHD), also known as ischemic heart disease or coronary artery disease, is a common term for the buildup of a waxy substance, called plaque, in the heart’s arteries, resulting in the failure of coronary circulation to supply adequate blood circulation to cardiac muscle and surrounding tissue, which can lead to a myocardial infarction (MI). Diabetes mellitus (DM) and coronary heart disease are the most common non-communicable diseases in the world, causing morbidity and mortality due to microvascular and macrovascular complications due to the close relationship between diabetes and vascular complications.