Title of article :
Familial Neuromyelitis Optica: A Case Report and Literature Review
Author/Authors :
Ebadi ، Zahra Multiple Sclerosis Research Center, Neuroscience Institute - Tehran University of Medical Sciences , Ghadiri ، Fereshteh Multiple Sclerosis Research Center, Neuroscience Institute - Tehran University of Medical Sciences , Asadollahzade ، Elnaz Multiple Sclerosis Research Center, Neuroscience Institute - Tehran University of Medical Sciences , Naser Moghadasi ، Abdorreza Multiple Sclerosis Research Center, Neuroscience Institute - Tehran University of Medical Sciences
Abstract :
Neuromyelitis Optica Spectrum Disorder (NMOSD) is an autoimmune rare disorder that involves the endfeet of astrocytes. The role of genetics in the disease is not well known. Rare cases of familial NMOSD were reported worldwide. In this report, first, we presented a young man with myelitis and his cousin who suffered from this disease. Then we reviewed some reports around the world about familial NMO. The prevalence of familial NMO is nearly 3%. First cases are reported from East Asia. Its characteristics are similar to the sporadic type. Recent data suggest genetics play role in NMO.
Keywords :
Neuromyelitis Optica (NMO) , Familial , Myelitis
Journal title :
Case Reports in Clinical Practice
Journal title :
Case Reports in Clinical Practice
