Title of article :
Current Perspectives and Future Prospects of mRNA Vaccines against Viral Diseases: A Brief Review
Author/Authors :
Koppu ، Vasavi Department of Veterinary Microbiology - ICAR-IVRI , Poloju ، Deepa Department of Veterinary Microbiology - ICAR-IVRI , Puvvala ، Bhavani Department of Veterinary Microbiology - ICAR-IVRI , Madineni ، Kavitha Department of Veterinary Microbiology - ICAR-IVRI , Balaji ، Shilpa Department of Veterinary Microbiology - ICAR-IVRI , Sheela ، Chandana Muraleedharan Pillai Department of Veterinary Microbiology - ICAR-IVRI , Manchikanti ، Sri Sai Charan Department of Veterinary Microbiology - ICAR-IVRI , Satpathy ، Moon Moon Department of Veterinary Microbiology - ICAR-IVRI
Abstract :
The mRNA vaccines replace our conventional vaccines (live-attenuated and inactivated vaccines) due to their high safety, efficacy, potency and low cost for their manufacturing. Since these many years the usage of these mRNA vaccines have been restricted as there are unstable and their low efficiency in in-vivo delivery. But now, these problems have been solved by recent technological advances. Many studies conducted in animal models and humans demonstrated the good results for the mRNA vaccines. This Review provides you a detailed overview of mRNA viral vaccines and considers the current perspectives and future prospects.
Keywords :
mRNA , vaccine , virus , lipid nanoparticle , codon optimization
Journal title :
International Journal of Molecular and Cellular Medicine(IJMCM)
Journal title :
International Journal of Molecular and Cellular Medicine(IJMCM)
