Title of article :
Circadian rhythm and body health: A review of the literatur
Author/Authors :
Eftekhar Vaghefi ، Shahrzad Sadat Department of Physiology and Pharmacology, Department of Basic Sciences - Pathology and stem cell Research center, Faculty of Medicine, Physiology Research Center, Institute of Neuropharmacology, Neuroscience Research Center - Kerman University of Medical Sciences , Malekpour Afshar ، Reza Pathology and stem cell Research center - Kerman University of Medical Sciences , Shahsavari ، Fatemeh Department of Biology - Faculty of Science, Neuroscience Research Center, Institute of Neuropharmacology - Shahid Bahonar University of Kerman , Mousavi ، Fatemeh Physiology Research Center, Institute of Neuropharmacology - Kerman University of Medical Sciences , Eftekhar Vaghefi ، Hossein Pathology and stem cell Research center - Kerman University of Medical Sciences , Nosratabadi ، Jafar Department of Basic Sciences - Faculty of Medicine - Islamic Azad University, Kerman Branch , Khaksari ، Mohammad Department of Physiology and Pharmacology - Kerman University of Medical Sciences , Soltani ، Zahra Department of Physiology and Pharmacology - Kerman University of Medical Sciences , Asadikaram ، Gholamreza Department of Biochemistry - School of Medicine - Kerman University of Medical Sciences , Shamsi Meymandi ، Manzoomeh Pathology and stem cell Research center - Kerman University of Medical Sciences , Raji Amir Hasani ، Alireza Department of Physiology and Pharmacology - Kerman University of Medical Sciences , Saheli ، Mona Department of Anatomical Sciences - Kerman University of Medical Sciences , Baghalishahi ، Masoumeh Department of Anatomical Sciences - Kerman University of Medical Sciences , Fekri Soofi Abadi ، Maryam Pathology and stem cell Research center - Kerman University of Medical Sciences , Mohammadizadeh ، Mahnaz Pathology and stem cell Research center - Kerman University of Medical Sciences , Dabiri ، Shahriar Pathology and Stem Cell Research Center - Kerman University of Medical Sciences
Abstract :
Circadian rhythm is a biological clock that regulates various physiological and pathological processes in the body. It is believed that any disturbance in circadian rhythm leads to impairment in some physiological systems, such as the endocrine, reproductive, renal, and cardiovascular systems. Various internal and external factors can alter circadian homeostasis and metabolism in a tissue-specific manner, and any disruption in these temporal interactions can result in the development of some chronic disorders. Circadian rhythm plays a crucial role in the pathogenesis of diseases, including cardiovascular disease, neurodegenerative disease, mood disorders, sleep disorders, diabetes mellitus, metabolism disorders, and cancer. This review aims to provide a brief overview of the basic circadian processes and an overview of current and future research directions in circadian rhythm and its related treatments.
Keywords :
Circadian rhythm , Physiology , Circadian Clock System , Chronotherapy , Circadian disruption
Journal title :
Physiology and Pharmacology
Journal title :
Physiology and Pharmacology
