Title of article :
The Effects of Cinnamon on Metabolic and Hormonal Status of Women With Polycystic Ovary Syndrome: A Randomized Controlled Trial
Author/Authors :
Hadipour ، Sanam Department of Midwifery and Reproductive Health - School of Nursing and Midwifery - Iran University of Medical Sciences , Amini ، Leila Department of Midwifery and Reproductive Health - School of Nursing and Midwifery, Nursing and Midwifery Care Research Center (NCRC) - Iran University of Medical Sciences , Afshar ، Bahare Department of Midwifery and Reproductive Health - School of Nursing and Midwifery - Iran University of Medical Sciences , Ghasemi ، Afsaneh Clinical Research Development Unit - Shahid Akbar Abadi Hospital, School of Medicine - Iran University of Medical Sciences , Haghani ، Hamid Department of Biostatistics - School of Public Health - Iran University of Medical Sciences , Sadeghi Avval Shahr ، Homa Department of Midwifery and Reproductive - School of Nursing and Midwifery - Iran University of Medical Sciences , Jahanfar ، Shayesteh Department of Public Health and Community Medicine - School of Medicine - Tufts University
From page :
53
To page :
64
Abstract :
Background: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of reproductive age. Accordingly, this study investigates the effect of oral capsules of cinnamon extract on the metabolic profile and hormonal status of women with PCOS. Methods: This blinded randomized clinical trial was performed on 66 women with PCOS referred to the gynecology and infertility clinics in Tehran City, Iran from 2016 to 2017. Eligible women were randomly allocated into intervention (n=33) and placebo (n=33) groups. The oral capsule of 3 g cinnamon extract was taken once a day for 12 consecutive weeks by the intervention group and the placebo capsule was given in the same way to the control group. Before and 12 weeks after starting the intervention, blood tests were performed to measure fasting blood sugar (FBS), fasting insulin (FI), triglycerides (TG), total cholesterol, low-density lipoprotein, high-density lipoprotein, total testosterone (TT), and sex hormone binding globulin (SHBG). The student t-test, paired t-test, chi-square test, and analysis of covariance were used to compare groups using the SPSS software, version 16. Meanwhile, P 0.05 were considered significant. Results: Consumption of cinnamon extract only leads to a significant decrease in total TT level compared to placebo (P=0.001), and has no significant effect on FBS, FI, TG, total cholesterol, low-density and high-density lipoprotein cholesterol, SHBG, and free androgen index (FAI). Conclusion: Cinnamon extract at a dose of 3 g/day for 12 consecutive weeks could decrease total TT in women with PCOS, and had no significant effects on metabolic and hormonal indicators in these women. Nevertheless, it is suggested that more studies be conducted with a larger sample size and various doses of cinnamon.
Keywords :
Herbal medicine , Polycystic ovary syndrome (PCOS) , Testosterone , Androgen , Cholesterol
Journal title :
Journal of Client-Centered Nursing Care
Journal title :
Journal of Client-Centered Nursing Care
Record number :
2780546
Link To Document :
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