Title of article :
Risk for Coronary Artery Disease and Morbid Preeclampsia: A Commentary
Author/Authors :
Roberta B. Ness، نويسنده , , Carl A. Hubel، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Pages :
8
From page :
726
To page :
733
Abstract :
Purpose A predisposition to coronary artery disease (CAD) may put women at risk for preeclampsia. Morbid preeclampsia (early, severe, recurrent, and with neonatal morbidity) represents the subset of preeclampsia of greatest public health concern. Methods We review here the published links between preeclampsia and CAD. Results Many risk factors are common to both CAD and preeclampsia. These include obesity; elevated blood pressure; dyslipidemia; insulin resistance; and hyperglycemia, together termed “Syndrome X”; as well as endothelial dysfunction; hyperuricemia; hyperhomocysteinemia; and abnormalities of inflammation, thrombosis, and angiogenesis. After pregnancy, women with preeclampsia are more likely to experience later life CAD. Conclusions Both the association between CAD risk factors and preeclampsia and the association between preeclampsia and later CAD appears to be more pronounced among the subset of women with morbid preeclampsia. Thus, women at elevated risk for CAD may be at particularly high risk for morbid preeclampsia and women with morbid preeclampsia may be those at highest risk for later life CAD.
Keywords :
hypertension , cardiovascular disease , Preeclampsia , diabetes. , low birthweight
Journal title :
Annals of Epidemiology
Serial Year :
2005
Journal title :
Annals of Epidemiology
Record number :
462667
Link To Document :
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