Title of article :
Mode of Delivery Is Associated With Asthma and Allergy Occurrences in Children
Author/Authors :
Muhammad T. Salam، نويسنده , , Helene G. Margolis، نويسنده , , Rob McConnell، نويسنده , , James A. McGregor، نويسنده , , Edward L. Avol، نويسنده , , Frank D. Gilliland، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2006
Pages :
6
From page :
341
To page :
346
Abstract :
Purpose A growing body of evidence indicates that perinatal factors modulate immune development and thereby may affect childhood asthma risk. In this study, we examined the associations between birth by cesarean section (C-section) and atopic disease occurrence in childhood. Methods Subjects were born in California between 1975 and 1987 and were 8 to 17 years old during their enrollment in the Childrenʹs Health Study. Our analysis was restricted to 3464 children born at or after 37 weeks of gestation with a birth weight of 2500 g or greater based on birth certificate data. Information about sociodemographic factors, reported physician-diagnosed asthma, and other atopic diseases was obtained by using a self-administered structured questionnaire. Logistic regression models were fitted to compute odds ratios (ORs) and 95% confidence intervals (CIs). Results Children born by C-section were at increased risk for asthma (OR, 1.33; 95% CI, 1.01–1.75), hay fever (OR, 1.57; 95% CI, 1.24–1.99), and allergy (OR, 1.26; 95% CI, 1.03–1.53) compared with those born vaginally. Risk associated with C-section was the same for children regardless of family history of asthma or allergy.
Keywords :
asthma , hay fever , allergy , Cesarean section , Mode of Delivery
Journal title :
Annals of Epidemiology
Serial Year :
2006
Journal title :
Annals of Epidemiology
Record number :
462728
Link To Document :
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