Title of article
Hyperthermia-induced cell death by apoptosisin myeloma cells
Author/Authors
S. Barni، نويسنده , , P. Pontiggia، نويسنده , , V. Bertone، نويسنده , , R. Vaccarone، نويسنده , , M. G. Silvotti، نويسنده , , E. Pontiggia، نويسنده , , G. Mathe، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2001
Pages
4
From page
170
To page
173
Abstract
We have analyzed by morphological (TEM) and histochemical (TUNEL reaction) criteria the type of cell death occurring in one case of human multiple myeloma after hyperthermia. Samples of cells examined immediately at the end of two treatments with a 15-day interval showed a significant degeneration, mostly demonstrating features of apoptosis (cell shrinkage, DNA fragmentation, karyorrhexis). The possible causes of the lag period between heating and apoptosis onset-expression are discussed.
Keywords
apoptosis / electron microscopy / hyperthermia / multiple myeloma / TUNEL
Journal title
Biomedicine and Pharmacotherapy
Serial Year
2001
Journal title
Biomedicine and Pharmacotherapy
Record number
477331
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