Title of article
T cell inactivation and cytokine deviation promoted by anti-CD3 mAbs
Author/Authors
Judith A. Smith، نويسنده , , Jeffrey A Bluestone، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1997
Pages
7
From page
648
To page
654
Abstract
Fc receptor nonbinding anti-CD3 monoclonal antibodies show promise for clinical application, in that they suppress graft rejection without the toxicity associated with conventional anti-CD3 antibody therapy. Recent studies suggest that the mechanism of soluble anti-CD3 antibody mediated immunosuppression involves partial signaling, induced cytokine deviation and Th1 cell inactivation.
Journal title
Current Opinion in Immunology
Serial Year
1997
Journal title
Current Opinion in Immunology
Record number
511658
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