Title of article
Radiolysis of 2-[18F]fluoro-2-deoxy-d-glucose (FDG) and the role of reductant stabilisers
Author/Authors
Richard M. Fawdry، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2007
Pages
9
From page
1193
To page
1201
Abstract
2-[18F]Fluoro-2-deoxy-d-glucose (FDG) is unstable at elevated temperatures, alkaline pH and in highly radioactive concentrated solutions. Radiolysis generates hydrogen peroxide in situ that accelerates the FDG decomposition rate and shortens the shelf life of the radiopharmaceutical. Reductant stabilisers slow down the decomposition rate and improve the shelf life for large-scale FDG manufacture in highly radioactive concentrated solutions.
Keywords
PET , FDG , radiolysis , Stabiliser
Journal title
Applied Radiation and Isotopes
Serial Year
2007
Journal title
Applied Radiation and Isotopes
Record number
548302
Link To Document