Title of article
The effects of contemporary use of coronary stents on in-hospital mortality
Author/Authors
Stephen E. Kimmel، نويسنده , , A. Russell Localio، نويسنده , , Ronald J. Krone MD، نويسنده , , Warren K. Laskey، نويسنده , , for the Registry Committee of the Society for Cardiac Angiography and Interventions، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2001
Pages
6
From page
499
To page
504
Abstract
OBJECTIVES
This study was designed to determine the effect of coronary stents on in-hospital mortality.
BACKGROUND
Despite extensive use of stents for percutaneous coronary interventions (PCIs), their effect on serious in-hospital events, especially mortality, is not well defined.
METHODS
A cohort study was performed using 16,811 consecutive native-vessel PCI procedures performed on patients in the Society for Cardiac Angiography & Interventions Registry from July 1, 1996, through December 31, 1998. Patients undergoing balloon-only angioplasty were compared with those receiving a planned or unplanned stent. Procedures with other devices were excluded. Multivariable analyses adjusted for detailed clinical characteristics and for individual laboratory.
RESULTS
Stents were associated with a significant reduction in in-hospital mortality (0.3%) compared with balloon procedures (0.6%; multivariable odds ratio [OR] 0.55; 95% confidence interval [CI] 0.34, 0.89; P = 0.014). The risk of emergency coronary bypass also was reduced by stenting (0.3% vs. 0.7%; multivariable OR 0.47; 95% CI: 0.29, 0.76; P = 0.002). Adjustment for the use of glycoprotein IIb/IIIa inhibitors did not change the results, and the effects of stenting relative to balloon procedures were similar in those procedures with and without glycoprotein IIb/IIIa blockade (p = 0.94).
CONCLUSIONS
This study suggests that coronary stenting, compared with balloon procedures, reduces in-hospital mortality, independent of the clinical setting.
Keywords
MI , OR , odds ratio , PCI , Percutaneous coronary intervention , SCA&I , Society for Cardiac Angiography and Interventions , myocardial infarction , CABG , CI , Confidence interval , coronary artery bypass grafting
Journal title
JACC (Journal of the American College of Cardiology)
Serial Year
2001
Journal title
JACC (Journal of the American College of Cardiology)
Record number
596385
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