Author/Authors :
Satoshi Gojo، نويسنده , , Shunei Kyo، نويسنده , , Shigeyuki Nishimura، نويسنده , , Nobuyuki Komiyama، نويسنده , , Nobutaka Kawai، نويسنده , , Masami Bessho، نويسنده , , Hiroshige Sato، نويسنده , , Toshihisa Asakura، نويسنده , , Motonobu Nishimura، نويسنده , , Kenji Ikebuchi، نويسنده ,
Abstract :
We describe a novel therapy of mononuclear cell transplantation combined with a left ventricular assist device (LVAD) for severe ischemic heart failure. Significant myocardial recovery by the LVAD rarely occurs in the severely failing heart. We undertook successful mononuclear cell transplantation in a patient who sustained an acute myocardial infarction that had resulted in the LVAD therapy. The heart regained good function after cell transplantation, and the LVAD was explanted 6 weeks later. These results suggest that this novel therapy could be an alternative to cardiac transplantation for severe ischemic heart failure.
