Title of article :
The Effect of Body Mass Index on the Outcome of IVF/ICSI Cycles in Non Polycystic Ovary Syndrome Women
Author/Authors :
Moini، Ashraf نويسنده , , Amirchaghmaghi، Elham نويسنده , , Javidfar، Nafiseh نويسنده , , Shahrokh Tehraninejad، Ensieh نويسنده , , Sadeghi، Maria نويسنده , , Khafri، Soraya نويسنده , , Shabani، Fatemeh نويسنده ,
Issue Information :
فصلنامه با شماره پیاپی 6 سال 2008
Abstract :
Background: The aim of this study was to investigate the effect of body mass index (BMI) on
the outcome of in vitro fertilization (IVF)/ intracytoplasmic sperm injection (ICSI) cycles in non
polycystic ovary syndrome (PCOs) women.
Materials and Methods: In this cross sectional study, 287 infertile non PCOs women referred to
Royan institute, Tehran, Iran between 2002 and 2003 were enrolled. Patients with age?40 years old
or BMI < 20 Kg/m2 were excluded. All of patients underwent IVF or ICSI cycles. The outcome of
assisted reproductive technology (ART) were compared between three groups: patients with 20?
BMI?25 (normal weight group); patients with 25 < BMI?30 (over weight) and patients with BMI
more than 30 Kg/m2 (obese group). ANOVA, T test, Chi-square and logistic regression were used for
analysis.P value less than 0.05 was considered as significant level.
Results: One hundred thirty three (46.3%) subjects had normal BMI, 117 women (40.8%) were
overweight and 37 women (12.9%) were obese. Obese group had lower pregnancy rate (13.5%)
in comparision to normal (29.3%) and overweight (21.4%) groups although this difference was
not statistically significant (p=0.09). Chi square analysis showed that normal weight women had
significantly higher regular mensturation (p=0.02). The logestic regression analysis showed that BMI
significantly affects on pregnancy rate of ART cycles in non PCOs women (p=0.038).
Conclusion: The finding of this study suggested that in non PCOs women, BMI had independent
adverse effect on the pregnancy rate of IVF/ICSI cycles.
Journal title :
International Journal of Fertility and Sterility
Journal title :
International Journal of Fertility and Sterility