The Consequences of Negative Energy Balance in Anorexia Syndrome

Study Objective Using four cases, this study describes common etiological factors and clinical sequelae in anorexia nervosa and athletic anorexia to present a biological explanation for interactions. Design Four anorectic girls were interviewed regarding their training programs and dietary intake. Bone mineral content, hormonal status, and energy intake were assessed during follow-ups. Results All the girls began training before puberty and had a low energy intake for age and height. Amenorrhea, low bone mineral content with stress fractures in three cases, and growth retardation in one case, were present at the follow-up after 6 years. Low amount of body fat and high serum cortisol is indicated and included in the discussion. The etiology is presented in an integrated model in addition to a biological explanation based on a negative energy balance, an acidic condition. Conclusion Energy deficits during puberty can result in the clinical sequela of the anorexia syndrome.