Title of article
The effect of Pyrrolo[3,4-c]carbazole derivatives on spinal cord ChAT activity
Author/Authors
David P. Rotella، نويسنده , , Marcie A. Glicksman، نويسنده , , J. Eric Prantner، نويسنده , , Nicola T. Neff، نويسنده , , Robert L. Hudkins، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1995
Pages
4
From page
1167
To page
1170
Abstract
Pyrrolo[3,4-c]carbazole derivatives were prepared as potential neurotrophic agents. The compounds were assayed for their ability to stimulate choline acetyltransferase (ChAT) activity in embryonic rat spinal cord cultures. These simplified K252a derivatives, although less potent and efficacious, have led to the identification of minimal structural requirements for K252a neurotrophic activity.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1995
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
787490
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