Title of article :
Platelet glycoprotein IIb/IIIa receptor antagonists derived from isoxazolidines
Author/Authors :
Pat N. Confalone، نويسنده , , Fuqiang Jin، نويسنده , , Shaker A. Mousa، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1999
Abstract :
A series of isoxazolidines has been synthesized as mimetics of the RGD sequence and was evaluated as antagonists of the platelet glycoprotein IIb/IIIa receptor. These compounds were shown to be highly potent GPIIb/IIIa antagonists, exhibiting submicromolar potencies.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters