Title of article
Structure-activity relationship of short-chain sphingoid bases as inhibitors of sphingosine kinase
Author/Authors
Steven De Jonghe، نويسنده , , Ilse Van Overmeire، نويسنده , , Samantha Poulton، نويسنده , , Chris Hendrix، نويسنده , , Roger Busson، نويسنده , , Serge Van Calenbergh، نويسنده , , Denis De Keukeleire، نويسنده , , Sarah Spiegel، نويسنده , , Piet Herdewijn، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
6
From page
3175
To page
3180
Abstract
Short-chain sphinganine analogues 8, 9, 18, and 19, as well as 3-fluoro-sphingosine analogues 25 and 26 were synthesized. Their potential as sphingosine kinase inhibitors was investigated, in combination with previously synthesized sphingosine and fluorinated sphinganine analogues.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1999
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790502
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