Title of article
A 3,4-Epoxypiperidine structure as a novel and simple DNA-cleavage unit
Author/Authors
Kazuyuki Miyashita، نويسنده , , Myunji Park، نويسنده , , Sayako Adachi، نويسنده , , Sayori Seki، نويسنده , , Satoshi Obika، نويسنده , , Takeshi Imanishi، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
3
From page
1075
To page
1077
Abstract
Based on the 4-hydroxy-1-azabicyclo[3.1.0]hexane structure of azinomycin, a 3,4-epoxypiperidine structure was designed as a novel and simple alkylating molecular unit, and some 3,4-epoxypiperidine derivatives were found to show DNA-cleavage activity, the structural requirements for which were revealed.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2002
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
792143
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