Author/Authors :
Xenia Beebe، نويسنده , , Angela M. Nilius، نويسنده , , Philip J. Merta، نويسنده , , Niru B. Soni، نويسنده , , Mai H. Bui، نويسنده , , Rolf Wagner، نويسنده , , Bruce A. Beutel، نويسنده ,
Abstract :
The parallel synthesis and antibacterial activity of 5-hydroxy[1,2,5] oxadiazolo[3,4-b]pyrazines is reported. The compounds were synthesized by condensing diaminofurazan with α-keto acids to give a variety of aryl-substituted analogues. Halogenated phenyl groups at C-6 give rise to the greatest Haemophilus influenzae antibacterial activity.
