Title of article
De novo synthesis of two new cytotoxic tiazofurin analogues with modified sugar moieties
Author/Authors
Mirjana Popsavin، نويسنده , , Ljilja Torovi ، نويسنده , , Vesna Koji ، نويسنده , , Gordana Bogdanovi ، نويسنده , , Sa a Spai ، نويسنده , , Velimir Popsavin، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
4
From page
3167
To page
3170
Abstract
A divergent synthesis of two novel tiazofurin analogues, 2-(3-deoxy-3-fluoro-β- -xylofuranosyl)thiazole-4-carboxamide (2) and 2-(3-acetamido-3-deoxy-β- -xylofuranosyl)thiazole-4-carboxamide (3), has been achieved starting from -glucose. Both nucleoside analogues were evaluated for their in vitro cytotoxicity against several human leukaemia and solid tumour cell lines.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2003
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
793530
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