Title of article :
Indoloprodigiosins from the C-10 bipyrrolic precursor: New antiproliferative prodigiosin analogs
Author/Authors :
Carmen M. Baldino، نويسنده , , Jonathan Parr، نويسنده , , Christopher J. Wilson، نويسنده , , Shi-Chung Ng، نويسنده , , Daniel Yohannes، نويسنده , , Harry H. Wasserman، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2006
Abstract :
The condensation of the C-10 methoxybipyrrole precursor (3) of prodigiosin with indoles and a related pyrrole derivative yields novel analogs of prodigiosin. Biological evaluation of these products revealed compounds that inhibit cancer cell proliferation from 50 nM to 50 μM.
Keywords :
pyrrole , Indole , Antiproliferative agent , prodigiosin
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
