Title of article
Synthesis of 4′-modified noraristeromycins to clarify the effect of the 4′-hydroxyl groups for inhibitory activity against S-adenosyl-l-homocysteine hydrolase
Author/Authors
Takayuki Ando، نويسنده , , Kenji Kojima، نويسنده , , Praveen Chahota، نويسنده , , Atsushi Kozaki، نويسنده , , Nikalje D. Milind، نويسنده , , Yukio Kitade، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2008
Pages
4
From page
2615
To page
2618
Abstract
4′-Modified noraristeromycin (NAM) analogs, 4′-sulfo-, 4′-sulfamoy, 4′-azido and 4′-amino-NAM, were systematically synthesized. The inhibitory activities of these analogs and related compounds against Plasmodium falciparum and human S-adenosyl-l-homocysteine hydrolase were investigated.
Keywords
Aristeromycin , Carbocyclic adenine nucleoside , S-adenosyl-l-homocysteine hydrolase , Plasmodium falciparum
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2008
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
799412
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