Title of article :
Studies on the structure–activity relationship of bicifadine analogs as monoamine transporter inhibitors
Author/Authors :
Mingzhu Zhang، نويسنده , , Florence Jovic، نويسنده , , Troy Vickers، نويسنده , , Brian Dyck، نويسنده , , Junko Tamiya، نويسنده , , Jonathan Grey، نويسنده , , Joe A. Tran، نويسنده , , Beth A. Fleck، نويسنده , , Rebecca Pick، نويسنده , , Alan C. Foster، نويسنده , , Chen Chen، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2008
Pages :
5
From page :
3682
To page :
3686
Abstract :
Compounds with various activities and selectivities were discovered through structure–activity relationship studies of bicifadine analogs as monoamine transporter inhibitors. The norepinephrine-selective 2-thienyl compound S-6j was efficacious in a rodent pain model.
Keywords :
pain , Structure–activity relationship , Monoamine transporters , Bicifadine , inhibitor , Selectivity , Potency
Journal title :
Bioorganic & Medicinal Chemistry Letters
Serial Year :
2008
Journal title :
Bioorganic & Medicinal Chemistry Letters
Record number :
799627
Link To Document :
https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=799627
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