Title of article :
α-S-GalCer: Synthesis and evaluation for iNKT cell stimulation
Author/Authors :
Marisa L. Blauvelt، نويسنده , , Maryam Khalili، نويسنده , , Weonjoo Jaung، نويسنده , , Janet Paulsen، نويسنده , , Amy C. Anderson، نويسنده , , Beth A. Whitaker and S. Brian Wilson ، نويسنده , , Amy R. Howell، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2008
Abstract :
The synthesis and evaluation for iNKT stimulation of α-S-galactosylceramide is reported. Prepared by alkylation of a galactosylthiol, this analog of the potent immunostimulatory agent, KRN7000, did not stimulate iNKT cells either in vitro or in vivo.
Keywords :
CD1d , iNKT cells , KRN7000 , ?-S-GalCer
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
