Title of article
Photochemical N-demethylation of alkaloids
Author/Authors
Justin A. Ripper، نويسنده , , Edward R. T. Tiekink، نويسنده , , Peter J. Scammells، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2001
Pages
3
From page
443
To page
445
Abstract
Certain alkaloids were observed to undergo N-demethylation processes under photochemical conditions. Tropine, acetyltropine, tropinone, and atropine were cleanly N-demethylated upon treatment with tetraphenylporphin, oxygen, and light. Dextromethorphan also underwent a N-demethylation reaction, but reacted further to afford an imine. In contrast, 14-acyloxycodeinones underwent a photochemically induced tandem N-demethylation–acyl migration.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2001
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
800367
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