مرکز منطقه ای اطلاع رساني علوم و فناوري -

چكيده لاتين :

Water mediated reactions offer useful and more environmentally friendly alternatives to their harmful organic solvent versions and have received increasing interest in recent years. Furthermore, water has unique physical and chemical properties, and by its utilization it would be possible to realize reactivity or selectivity that cannot be attained in organic solvents. Polyacrylamide supported phenolate is synthesized, characterized, and introduced as a new basic heterogeneous catalyst for aza-and thio-Michael addition reactions of both aliphatic and aromatic amines and thiols to a ,B-unsaturated electrophiles in aqueous media at room temperature. Di-thio-Michael addition of dithiol was performed successfully. Results showed that thio-Michael addition is faster than aza-Michael addition due to higher nucieophilicity of thiolate anion in comparison with neutral amino functionality. Mild reaction condition, low catalyst/substrate ratio, high efficiently, and reusability make this new basic heterogeneous catalyst as one of few reported polymer supported catalysts for aza-and thio-Michael reactions in green aqueous media.