چكيده لاتين :
Data available implies that certain systemic
chronic inflammatory disorders
and a few pulmonary diseases affect
testosterone (T) biosynthesis . The
status of free testosterone (FT) has not yet be en
determined in sulfur mustard(SM) induced
chronic persistent asthma in Iranian veterans for
the long term effects. The aim of the study was
to assess the status of FT levels on SM induced
asthma patients and to compare it with that of
non-exposed asthmatics and healthy subjects;
our goal was also to determine the frequency of
hypogonad hypogonadism in the target population.
Marerials and Methods: Protocol of study was
based on random selection of target population
using a self-report questionnaire, physician diagnosed
asthma, and ratification of SM exposure.
Two control groups, age and sex-matched,
were enrolled accordingly as the non-exposed
asthma and healthy subjects respectively . Serum
samples of FT, Follicole Stimulating Horm one
(FSH), and Luteinizing Hormone (LH) were
measured and documented.
Results: Forty-three male, war veterans, exposed
to chemical warfare were enrolled as the case
group, mean age 53.95±6.80 years. The mean serum
FT levels were 15.70±10.54 pglmL, the levels
of 32.6% of subjects being bel ow the lower normal
range. The mean serum values of FSH, LH,
