چكيده لاتين :
Background: Obsessive-compulsive disorder typically begins early in life and has a chronic
course. Despite the need for long-term treatment, the information about therapeutic effect on
different clinical subtypes is limited.
Methods: Consecutive outpatients with obsessive-compulsive disorder were evaluated for
response to a two-month fluoxetine therapy course by Yale-Brown obsessive -compulsive scale
according to the clinical subtype of the disease.
Results: Of 265 patients, fluoxetine significantly decreased the symptoms in general. The mean
Yale-Brown obsessive- compulsive scale in washers and patients with obsessive thoughts was
significantly decreased after the intervention. The decrease in Yale-Brown obsessive- compulsive
scale in checkers was not statistically significance.
Conclusion: Fluoxetine has sustained efficacy on patients with obsessive-compulsive disorder
and is generally well tolerated. Fluoxetine has greater efficacy on washers and on obsessive
thoughts than checkers.
