چكيده لاتين :
Background : Although numerous studies have round deleterious effects of inbreeding on childhood and pre-reproductive
mortality, one question remains inadequately addressed: Dose inbreeding lead to increased chi ldhood mortality rates in
countries with high level of consanguinity?
Methods: To evaluate the public health impact of inbreeding on offspring
mortali ty, the association between mean of inbreeding coeffi cient (alfa) and sex specific child and adult mortal ity rates in 24
countries from Asia and Africa was analyzed. Results: Statist ical analysis showed that countries with relatively higher rates
of consanguineous marriages have higher mortality rates than the countries with lower consanguinity rates. Iso, countries
with relatively higher GOP per capita have lower mortality rates. After controlling the GOP per capita, significant positive
correlations between alfa andchild (Female: r=0,4355, dt= 21, P=0 .038; Male: r=0.3991, df=21, P=0.059) mortality rates were
observed. There was no significant correlation between alfa and adult (Female: r=0.2977, df=2 1, P=O.J68; Male: r=0.2207,
df=2 1, P=0.312) mortality rates, after controlling for GOP percapita . Conclusion : It is coneluded that consangu inity influences
ehild deaths rate independent of the GOP per capita and that a large proportion of deaths could be attributed to
inbreeding in several countries due to high frequencies or consanguinity.
