چكيده لاتين :
Intravenous lipid solution (intralipid) provides essential substances
for optimizing growth in premature infants, but has
potential side effects. We investigated the effects of dermal
application of sunflower-seed oil (SFSO) as a substitute for
intralipid in preterm infants. This study comprised of 20 preterm
infants, unable to be fed enterally divided into case and
control groups of equal numbers. SFSO was rubbed over the
whole skin (1 gr/kg, three times daily) in case group only. Serum
triglyceride and cholesterol levels were measured in both
groups initially, and on the third and seventh day. The initial
mean of serum triglyceride (TG) levels in the case and control
groups were 42.6± 15.5mg/dl and 45.2±) 4.0 mg/dl respectively.
TG level had a steady state increase at three (47%) and
seven (80%) days of cutaneous application of SFSO in the
casegroup, whereas, it decreased steadily in the control group.
The respective initial mean cholesterol levels in the study and
control groups were 94.6 and 102.5 mg/dl which did not significantly
change during the course of the study in both
groups. This study is indicating that although, deficiency of
essential fatty acids or their related clinical complications
were not observed in either group, appl ication of SFSO steadily
improved the level of triglyceride in preterrn infants.
Therefore, dermal application of sunflower-seed oil is a noninvasive
and economic way, and it appears to be a suitable
non-complicated alternative for intralipid.
