پديد آورندگان :
Zamani Moghadam Abdolkarim نويسنده , Nazem Habibolla نويسنده , Karimi Iraj نويسنده , Abolhasani Darani Izad نويسنده , Hassanpour Hossein نويسنده
چكيده لاتين :
To clarify the effects of Creatine Monohydrate (CrM) supplementation on growth performance and to evaluate histopathological lesions in rats and broiler chickens. Two species of animals, chickens and rats
were maintained on standard conditions. Each of species (thirty six rats and thirty six chickens), were separated into three equal groups of twelve animals. The control group receiving no CrM while the experimental groups received CrM added to the water supply to achieve a dose of 0.25 and 0.5 g kg-1 day". The body weight and feed intake were measured and feed conversion rate was calculated. All animals were dissected after 15 days; Portions of liver, kidney, skeletal muscle, were separated and prepared for histopathological sections.
There were not any significant variations in body weight gain and feed conversion rate between control and creatine-supplemented groups in rats. There were not also any change in feed conversion rate in
chickens but body weight gain significantly (p<0.05) increased at day 15 of rearing in creatine-supplemented group (0.5 g kg" day") compared to its control. Histopathological changes were not significant in two species. This study showed that creatine do not have any pathological effect on liver, kidney and muscle of rats and chickens and can improve body weight gain in rearing chickens.
