چكيده لاتين :
Lactoferrin (LF) has antimicrobial properties against bacteria, fungi and several
viruses including herpes virus, HIV and hepatitis C virus.
The aim of this study was to detect LF in PMNs and plasma of the patients
suffering from hepatitis C and the healthy persons.
The sonicated solutions of PMNs of two groups were evaluated by SDS-PAGE
(10%), isoelectric focusing (30%) and dot blotting .The level of LF in plasma was
measured by ELISA.
The results confirmed the presence of LF in PMNs of the two groups. ELISA
showed that the level of LF in plasma of patients was higher than normal persons.
Based on these findings we conclude that not only the production of LF was not
reduced in the patients but also its level was significantly increased compared with the
normal persons(P<0.0001).
