پديد آورندگان :
Fallah-Tafti Saeid نويسنده , Marashian Mehran نويسنده , Faridian-Eragh Delara نويسنده , Mansouri Seyed-Davood نويسنده , Masjedi Mohammad-Reza نويسنده
چكيده لاتين :
The tetrad of bronchial asthma, severe sinusitis, nasal polyp, eosinophilia, and systemic
vasculitis is the main feature of allergic granulomatosis and angitis (Churg- Strauss Syndrome).
This vasculitis is usually seen idiopathic in patients with a long history of asthma; oral steroids
using steroid inhalers, vaccination and desensitization might be triggering factors. Drugs such as
leukotriene receptor antagonists (LTRAS), penicillin, sulphonamides, anticonvulsants and
thiazides have also been implicated. By presenting the cases in this article, the authors suggest
that some cases of CSS may be partially or totally suppressed by corticosteroid therapy of
asthma for long periods and replacing oral steroid by inhaler will reveal a pathologic condition
of CSS, called frustes CSS forms.
We report three subjects with asthma who had been receiving previously multiple
corticosteroid courses for control, but when systemic corticosteroids were discontinued or
switched over to steroid inhaler, the patients developed a similar syndrome.
