Preventive Role of Olive Oil On Serum Lipid Profile and Antioxidant Status of Methionine Overload Rabbits (Part II)

This study was designed to show the possible preventive role of olive oil on serum lipid profile and antioxidant status of methionine overload rabbits. Thirty adult male rabbits were divided into three equal groups (10/group) and treated as follows for eight weeks: first group (GI) was intubated orally with tap water and served as control group, animals in the second group were intubated daily with 100mg/kg B.W. of methionine (GII), while rabbits in the third group were intubated daily with 100mg /kg B.W of methionine for four weeks and then after intubated orally with 0.51 ml /kg B.W/ of olive oil daily for further four weeks (GIII). Fasting blood samples were collected at zero, four and eight weeks of the experiment for measuring serum total cholesterol (TC), triacylglycerol (TAG), low density lipoprotein(LDL-C ),very low density lipoprotein(VLDL-C), high density lipoprotein (HDL-C), glutathione (GSH) and Malondialdehyde (MDA) concentrations .The results of this experiment showed the preventive role of olive oil in alleviation of hyperlipidemia and oxidative stress induced by methionine overload.