Prevalence of Ventilator-associated Pneumonia (Vap) in Iran; A met analysis study

Background and objective: Pneumonia known as a common, serious and cost-consuming complication among hospitalized patients in intensive care wards. Ventilator Associated Pneumonia usually occurred after 48 hours of intubation and mechanical ventilation. Regarding to mortality rate of VAP that reported 30-70% there is need epidemiological study on this case of Pneumonia. Materials and Methods: By using search the keywords in information Databases such as SID, Magiran, Iranmedex, Sciencedirect, Pubmed and Google Scholar, a total number of 10 papers were selected between 1374-1391 years, according to approaches to enrolled in study. All papers after qualitative control by using random effect model enrolled to Meta analysis. Heterogeneity between studied was assessed by I-Square index, and then data were analyzed by using R software (Version 2.11.1) and STATA software (version 10). Findings: Among 40 selected paper, 10 ones included in this study which totally involved 1043 persons. VAP infection had 33% prevalence in Iran(CI:95%:20-47). Entrobacter by 27% prevalence (CI:95%: 20-47) was most frequent agent of VAP while Staphylococcus epidermidis by 4% as lowest frequent agent played role(CI:95%:2-52). Conclusions: According to importance of VAP as hospital acquired infection and high mortality of this kind of .Pneumonia there is necessity to monitoring VAP infection and its antibiotic resistance pattern