Comparison between propofol and Ketamine anesthesia on arterial blood pressure and vital signs in dog

Introduction: The aim of this study was to compare between propofol and ketamine anesthesia on arterial blood pressure, heart rate, temperature and respiratory rates in dogsMaterial and method: For this study total of 10 dog with a weight-range of 22.6±5.7 Kg with the mean age of 12 months, where selected and randomly divided into two group. The first group received 8mg/kg propofol 1% and maintained by continuous propofol 0.3 mg/kg/min and the second group received 10mg/kg ketamine for induction and 0.8mg/kg/min for maintenance. All baseline measurements were obtained before induction (time 0) and 5, 10, 15, 30, 45, 60 and 90 minutes after induction. For arterial blood pressure measurements an intravenous catheter was inserted in femoral artery. And data were analyzed via ANOVA, with a significant level P 0.05.Result: The result of this study shows that Increase of HR in ketamine group was significantly more than propofol group (P 0.05). Respiratory rate (RR) in both groups decrease until 45 min after induction and then increase, but difference between two groups was statistically not significant (P 0.05). Also, the mean of rectal temperature decrease in ketamine group was less than that of propofol group, a difference which was statistically not significant (P 0.05). After induction of anesthesia, hypertension in both groups observed, that significantly more in ketamine group (P 0.05). Conclusion: Our study has shown propofol could maintain blood pressure in normal range and has better function in comparison with ketamine.