IGF-1 – GH, HPA AXIS, Body Composition and Strength changes to chronic supplementation with β-Hydroxy- β-Methyl Butyrate (HMB) And Complex Training in Elite Basketball Players Aged 19-26 Years Old

BACKGROUND: Basketball is an activity that contributed from alternative energy systems is highly correlated with the explosive power of lower body and muscular strength of athletes and production of high levels of power in the shortest period of time (power), is introduced as necessary to achieve optimal performance in the sport (6). To achieve the highest performance in this field of sport, taking advantage of complex training and ergogenic supplement beta-hydroxy-beta-methyl-butyric acid(HMB) for its anabolic and anti-catabolic traits, seems to make it available; therefore, the aim of this study was to investigate The Interaction and Exclusive Effect Of 8 Week β-Hydroxy- β-Methyl Butyrate (HMB) Supplementation And Complex Training On Body Composition, Strength And Hypertrophic/Atrophic Factors Of Elite Basketball Players Aged 19-26 Years Old. METHODS: In this semi-experimental, randomized, double-blind, placebo-controlled study with pre-test and post-test design, 40 male basketball players of Division 1 Basketball League aged 26-19 years were selected and randomly divided into four groups of 10 people, including: (1) Training-supplements(HMB), (2)Training-placebo group,(3)supplement(HMB) and (4) control group. Complex training protocols was performed in 8 weeks through 3 times a week (on odd days), on a regular basis by 60% to 80% of 1RM by all four groups, while at the same time four group attended their regular basketball trainings on 3 days of week (on even days). Data’s were expressed as mean (±SD) and analysis of variance (ANOVA), Bonferroni post hoc tests to evaluate differences between the four groups (for difference between groups) and dependent sample T-test for comparing the result of intra-group in different types in various times at the significant level of p 0.05was performed. All statistical assessments were assessed by SPSS software (21v). RESULTS: The findings of this study showed that supplementation with HMB, complex training and having both of these two factors through a chronic protocol, resulting in anabolic stimulus for a significant increased levels of IGF-1 and GH ratio, (p 0.05), lean body mass (p 0.05) Based on BIA estimates and the percentage of upper and lower body strength (p 0.05), so that the process of the increase in supplementary-Training group was observed more than other groups, all these values was higher in the training group in comparison to supplement group as well. In turn, cortisol serum levels were decreased in same hierarchy of groups. CONCLUSIONS: Beta-hydroxy-beta-methyl butyrate supplementation and complex training separately contributed to preservation of muscle mass and strength increase and also lead to deliver anabolic and anti-catabolic effects but the study indicates that the interaction of the these two factors might lead to a synergistic effect on athletes especially when its applied in some specific periods of athlete s season where there are high-intensity training periods. The results of this study suggests that complex training along with HMB consumption could be beneficial for attenuating tissue catabolism and initiate muscle anabolism particularly in athletes.