Gökay, S Sağlık Bakanlığı - Ankara Eğitim ve Arastırma Hastanesi - Çocuk Sağlığı ve Hastalıkları, Turkey , Tıras, Ü Sağlık Bakanlığı - Ankara Eğitim ve Arastırma Hastanesi - Çocuk Sağlığı ve Hastalıkları, Turkey , Simsek, E Sağlık Bakanlığı - Ankara Eğitim ve Arastırma Hastanesi - Çocuk Sağlığı ve Hastalıkları, Turkey , Yasıtlı, U Sağlık Bakanlığı - Ankara Eğitim ve Arastırma Hastanesi - Çocuk Sağlığı ve Hastalıkları, Turkey , Dallar, Y Sağlık Bakanlığı - Ankara Eğitim ve Arastırma Hastanesi - Çocuk Sağlığı ve Hastalıkları, Turkey

Leptin and body mass index correlation in patients with meningomyelocele

14685

Aim: We aimed to determine the plasma leptin levels and the relationship between plasma leptin level and body mass index in patients with meningomyelocele.Material and Methods: Between the years 2008-2009, thirty patients who were previously diagnosed with meningomyelocele and 30 healty control group were enrolled for this study. The gender, age, weight, heigt, body mass index, presence of hydrocephalus, weight, heigt, body mass index percentiles according to age and gender were noted. Serum leptin levels were studied in both the patients and control group. Results: The mean age of patients was 42.1± 27 months and control group was 44.8±25 months. There was no significant difference between the patients and the control group in terms of body mass index which was 95% (p=0.052). The median leptin level was 0.1 ng/ml (0.04-7.8) in patients with a body mass index of 95%, 0.07 ng/ml (0.04-7.8) and in patients with body mass index of 95% and 0.04 ng/ml (0.04-0.8) in the control group. While there was no significant difference in leptin levels between the patients with body mass index 95% and 95% (p=0.055), leptin levels were determined significantly higher in all patients with any body mass index than in the control group (p 0.01). There was no relation between the precence of hydrocephalus and body mass index percentile. Leptin levels were not significantly different between the patients with or without hydrocephalus.Conclusion: Determination of higher leptin levels in meningomyelocele patients with any body mass index shows that anatomical abnormalities other than hydrocephalus may cause disorders in transport of leptin to the central nervous system.

119

Meningomyelocele , body mass index , child , leptin

Ege Journal Of Medicine

123