ceviker, kadir university of suleyman demirel - faculty of medicine - department of cardiovascular surgery, Turkey , sahinalp, sahin van regional trainingand research hospital - department of cardiovascular surgery, Turkey , yazkan, rasih university of suleyman demirel - faculty of medicine - department of thoracic surgery, Turkey

Topographic features of extracorporeal circulation circuit surface observed by atomic force microscopy; coated or non-coated?

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Objective: Polymer based materials used in the manufacture of extracorporeal circulation (ECC) circuit that is the main part of the heart lung machine used in cardiac surgery, poses the unavoidable inflammatory and coagulation reactions because of the contact with the tissue and biological fluids particularly the blood. The reason for these reactions may include chemical properties of the material used but the surface properties of the contact surface are also important. Atomic force microscopy (AFM) is useful method to analyze the surface morphology of a thin line and obtain information about the thickness, roughness and height asymmetries values such as the skewness and kurtosis of the line. The aim of the study is demonstrating the ECC circuits’ topographic features that hypothesized as one of the main reason for side effect reactions as inflammation and coagulation.

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Atomic force microscopy , extracorporeal circulation circuits , kurtosis , Polymer biomaterial , Skewness

Medical Journal Of Suleyman Demirel University

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