Author/Authors
Kaymak, Ayşegül Öztürk Ministry of Health - Dr A Y Demetevler Oncology Education and Research Hospital, Turkey , Sönmez, Çiğdem Ministry of Health - Dr A Y Demetevler Oncology Education and Research Hospital, Turkey , Çavdarlı, Büşranur Ministry of Health - Numune Education and Research Hospital, Turkey , Öztomurcuk, Senem Ministry of Health - Dr A Y Demetevler Oncology Education and Research Hospital, Turkey , Talayhan, Nurefsan Ministry of Health - Dr A Y Demetevler Oncology Education and Research Hospital, Turkey , Guntaş, Gülcan Ministry of Health - Dr A Y Demetevler Oncology Education and Research Hospital, Turkey
Title Of Article
The Importance of Test Variability in Acute Myeloblastic Leukemia: A Case Report
شماره ركورد
18976
Abstract
Acute myeloid leukemia (AML), phenotypically and genotypically is a quite heterogeneous disease. More than 100 cytogenetic aberrations and gene mutations that are specific to this disease are defined (1). A patient who applied to hematology polyclinic of our hospital with various complaints was diagnosed with AML. In genetic analyses, t(8;21) and FLT3-ITD were found to be positive. Additionally, in chromosome analysis trisomy 8 was observed. After remission was ensured in the patient, allogenic stem cell transplantation was carried out. By conducting t(8;21), FLT3 mutation and trisomy 8 analyses on the patient at regular intervals, prior information was gathered about the relapse and minimal residual disease.
From Page
146
NaturalLanguageKeyword
Minimal Residuel Disease, acute myeloid leukemia, chimerism, trisomy 8, FLT3 mutation, t(8 , 21)
JournalTitle
Gazi Medical Journal
To Page
148
JournalTitle
Gazi Medical Journal
Link To Document