Author/Authors :
Yıldız, Fatih Cukurova University - Faculty of Medicine - Department of Rheumatology-Immunology, Turkey , Taş, Didem Arslan Cukurova University - Faculty of Medicine - Department of Rheumatology-Immunology, Turkey , Özyılmaz, Ezgi Cukurova University - Faculty of Medicine - Department of Pulmonology, Turkey , Evran, Mehtap Cukurova University - Faculty of Medicine - Department of Endocrinology, Turkey , Karakoç, Emre Cukurova University - Faculty of Medicine - Department of Intensive Care Unit, Turkey , Zorludemir, Suzan Cukurova University - Faculty of Medicine - Department of Pathology, Turkey , Erken, Eren Cukurova University - Faculty of Medicine - Department of Rheumatology-Immunology, Turkey
Abstract :
Polymyositis is a systemic, inflammatory muscle disease. Respiratory insufficiency as a result of respiratory muscle involvement could also be observed. Here we report a fortyone-year-old man who attended to the hospital with the complaints of shortness of breath and chest pain that have suddenly started. Physical examination has revealed proximal muscle weakness. Serum creatinine phosphokinase level has increased, ANA was positive and the electromyographic examination has revealed myopathic changes. Deltoid muscle biopsy was in accordance with polymyositis. Methyl-prednisolone 1 gram iv pulse therapy was given during the first 5 days. He was started with 25 mg/week parenteral methotrexate. Laboratory tests suggested hypothyroidism and levothyroxine replacement therapy was started. The clinical findings have improved concomitant with the reduction in the muscle enzymes and thyroid stimulant hormone levels into the normal ranges. He was discharged with the recommendation of the NIMV device application during night-time. The clinical symptoms are more severe in the presence of alveolar hypoventilation due to polymyositis and coincidantal hypothyroidism.
NaturalLanguageKeyword :
Alveolar hypoventilation , non invasive mechanical ventilation , hypothyroidism , polymyositis
