Koyuncu, Güner Çelik Beyhekim Devlet Hastanesi - Nöroloji Bilim Dalı, Turkey , Ünler, Gülhan Kanat Başkent Hastanesi - Konya Uygulama ve Araştırma Merkezi - Gastroenteroloji Bilim Dalı, Turkey , Göktürk, Hüseyin Savaş Başkent Hastanesi - Konya Uygulama ve Araştırma Merkezi - Gastroenteroloji Bilim Dalı, Turkey

A recurrence of Guillain-Barré syndrome or a case of acute-onset chronic inflammatory demyelinating polyneuropathy in the course of chronic hepatitis B?

24258

Chronic inflammatory demyelinating polyneuropathy is a demyelinating polyneuropathy characterized by distal/proximal weakness, which shows gradual progression over a period of 8 weeks or longer. Guillan-Barre Syndrome is a condition characterized by acute monophasic paralysis typically following an infectious assault, and it usually peaks in severity over 3-4 weeks at most. Although rare, there are acute-onset chronic inflammatory demyelinating polyneuropathy cases that show progression over a period shorter than 4 weeks, as is the case in Guillan-Barre Syndrome .This report discusses a case of chronic inflammatory demyelinating polyneuropathy in a HBsAg-positive patient, which started as Guillan-Barre Syndrome but showed 3 recurrences within 6 months, each with rapidly progressing quadriplegia, respiratory arrest, and elevated liver enzymes and HBV DNA.

782

Hepatitis b , polyneuropathy , antiviral therapy

Cukurova Medical Journal

786