Author/Authors
Gelincik, Hakan Çukurova University - Faculty of Medicine - Department of Pediatric Oncology, Pediatric Bone Marrow Transplantation Unit, Turkey , Küpeli, Serhan Çukurova University - Faculty of Medicine - Department of Pediatric Oncology, Pediatric Bone Marrow Transplantation Unit, Turkey
Title Of Article
Long term survival in a patient with recurrent metastatic Ewing sarcoma treated with irinotecan and temozolomide
شماره ركورد
24285
Abstract
Ewing sarcoma family of tumor is the second most common bone tumor in children and young adults, after osteosarcoma. Different chemotherapeutic regimens are used in treatment of relapsed/recurrent Ewing sarcoma. Promising results were achieved with combination of irinotecan and temozolomide. Our case was a 13-year-old female with relapsed Ewing sarcoma and after 12 cycles of irinotecan (20 mg/m2/10 days) and temozolomide (100mg/m2/5 days) treatment she had not any complaints, and her radiological lesions remained stable for 66 months. Irinotecan and temozolomide have been used successfully in treatment of relapsed/recurrent Ewing sarcoma, but there is a need for randomized prospective studies with larger patient groups for establishing the efficacy of this treatment protocol.
From Page
811
NaturalLanguageKeyword
Ewing Sarcoma , irinotecan , temozolomide
JournalTitle
Cukurova Medical Journal
To Page
814
JournalTitle
Cukurova Medical Journal
Link To Document