Tayman, Cüneyt Fatih Üniversitesi - Tıp Fakültesi - Çocuk Sağ ve Hast Anabilim Dalı, Turkey , Tonbul, Alparslan Fatih Üniversitesi - Tıp Fakültesi - Çocuk Sağ ve Hast Anabilim Dalı, Turkey , Soylu, Gül Güner Fatih Üniversitesi - Tıp Fakültesi - Mikrobiyoloji Anabilim Dalı, Turkey , Akça, Halise Fatih Üniversitesi - Tıp Fakültesi - Çocuk Sağ ve Hast Anabilim Dalı, Turkey , Çatal, Ferhat Fatih Üniversitesi - Tıp Fakültesi - Çocuk Sağ ve Hast Anabilim Dalı, Turkey

Resistance of group A beta Haemolytic streptococcus isolated from children with tonsillopharyngitis against commonly used antibiotics

26478

Objectives: We aimed to assess the antimicrobial susceptibility (penicillin, amoxicillin-clavulanate, amoxicillin and azithromycin), of A group beta haemolytic streptococci (AGBHS) isolated from children with tonsillopharyngitis. Materials and methods: AGBHS were isolated from throat swaps cultures according to CLSI criteria from children aged 5 to 15 years who applied to the Pediatric outpatient policlinics with complaints of high fever, sore throat and difficulty in swallowing. Antimicrobial susceptibilities were assessed. Susceptibilities of isolates to penicillin, amoxicillin-clavulanate, amoxicillin and azithromycin were determined by disk diffusion method. Results: AGBHS were isolated from 216 (26,3%) of 821 of throat swaps cultures samples. Amoxicillin-clavulanate was found to be the most sensitive antibiotic with a sensitivity of 99,5%, which was followed by amoxicillin (95,8%), penicillin (95,3%), and azithromycin (78,7%) (p 0.05). However, 21.3% percent of the bacteria were found to be resistant to azithromycin. Conclusion: Amoxicillin-clavulanate was found to be the most sensitive antibiotic, and AGBHS isolates were found to be highly resistant to azithromycin. The resistance to azithromycin can be decreased by preventing unnecessary use of this antibiotic in children with tonsillopharyngitis.

305

Group A beta haemolytic streptococci , tonsillopharyngitis , antimicrobial susceptibility , azithromycin , children

Dicle Medical Journal

308