Öner, Ender Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Hospital - Cardiology Department, Turkey , Görgülü, Şevket Acıbadem University - Cardiology Department, Turkey , Aksu, Hale Ünal Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Hospital - Cardiology Department, Turkey , Baycan, Ömer Faruk Muş State Hospital - Cardiology Clinic, Turkey , Ertürk, Mehmet Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Hospital - Cardiology Department, Turkey , Çelik, Ömer Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Hospital - Cardiology Department, Turkey , Satılmışoğlu, Hulusi Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Hospital - Cardiology Department, Turkey , Aksu, Hüseyin Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Hospital - Cardiology Department, Turkey

GRACE and TIMI scores in predicting the extension of coronary artery disease in patients with non-ST elevation myocardial infarction

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Objective: We aimed to assess the correlation of TIMI and GRACE risk scores with the SYNTAX score as the surrogate of severity and extent of coronary artery disease. Methods: Patients with non-ST elevation myocardial infarction admitted to our emergency department and undergoing coronary angiography were considered for this study. TIMI and GRACE risk scores were calculated, and coronary artery disease severity and extension were assessed by using the SYNTAX score algorithm. Results: We assessed 145 patients (mean age 59.41±11.04 years, 29% female). Based on the GRACE risk score for in-hospital deaths, the SYNTAX risk score was 12.22±8.70 for the low-risk group, 16.66±8.01 for the intermediate-risk group, and 22.48±11.42 for the high-risk group (ANOVA, p 0.0001). There were significant positive correlations between the SYNTAX score and GRACE scores (r=0.414, p 0.0001). The SYNTAX score also had a significant but weaker correlation with the TIMI score (r=0.271, p=0.001). The GRACE score showed good discriminatory capacity between the patients with and without a high-risk ( 33) SYNTAX score, with an area under the ROC curve of 0.804 (CI 0.660-0.948, p=0.002); however, the TIMI score showed no predictive capacity and had an area under the ROC curve of 0.532 (CI 0.358- 0.749, p=0.749). Conclusion: A GRACE score indicating high risk may be helpful in predicting patients with severe extended coronary artery disease

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Coronary artery disease , non , ST elevation myocardial infarction , risk scores

Dicle Medical Journal

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